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PTRH2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y3E5 |
| Other Accession | NP_057161.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19194 Da |
| Antigen Region | 26-55 aa |
| Gene ID | 51651 |
|---|---|
| Other Names | Peptidyl-tRNA hydrolase 2, mitochondrial, PTH 2, Bcl-2 inhibitor of transcription 1, PTRH2, BIT1, PTH2 |
| Target/Specificity | This PTRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTRH2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PTRH2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PTRH2 |
|---|---|
| Synonyms | BIT1, PTH2 |
| Function | Peptidyl-tRNA hydrolase which releases tRNAs from the ribosome during protein synthesis (PubMed:14660562). Promotes caspase- independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1. |
| Cellular Location | Mitochondrion outer membrane; Single-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
References
Fan, T., et al. Int. J. Oncol. 35(2):359-367(2009)
Biliran, H., et al. J. Biol. Chem. 283(42):28029-28037(2008)
Bouchentouf, M., et al. Am. J. Transplant. 7(6):1491-1505(2007)
Jan, Y., et al. Cell 116(5):751-762(2004)
De Pereda, J.M., et al. J. Biol. Chem. 279(9):8111-8115(2004)
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