PCOLCE2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9UKZ9 |
Other Accession | NP_037495.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45717 Da |
Antigen Region | 201-230 aa |
Gene ID | 26577 |
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Other Names | Procollagen C-endopeptidase enhancer 2, Procollagen COOH-terminal proteinase enhancer 2, PCPE-2, Procollagen C-proteinase enhancer 2, PCOLCE2, PCPE2 |
Target/Specificity | This PCOLCE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human PCOLCE2. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PCOLCE2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PCOLCE2 |
---|---|
Synonyms | PCPE2 |
Function | Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1. |
Cellular Location | Secreted. |
Tissue Location | Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage |
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Provided below are standard protocols that you may find useful for product applications.
Background
PCOLCE2 binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
References
Zhu, J., et al. J. Lipid Res. 50(7):1330-1339(2009)
Steiglitz, B.M., et al. J. Biol. Chem. 277(51):49820-49830(2002)
Steiglitz, B.M., et al. Cytogenet. Cell Genet. 95 (3-4), 244-245 (2001) :
Xu, H., et al. Genomics 66(3):264-273(2000)
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