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CHSY3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q70JA7 |
| Other Accession | Q5DTK1, NP_787052.3 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100284 Da |
| Antigen Region | 531-560 aa |
| Gene ID | 337876 |
|---|---|
| Other Names | Chondroitin sulfate synthase 3, Carbohydrate synthase 2, Chondroitin glucuronyltransferase 3, Chondroitin synthase 2, ChSy-2, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3, N-acetylgalactosaminyltransferase 3, CHSY3, CHSY2, CSS3 |
| Target/Specificity | This CHSY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human CHSY3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHSY3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHSY3 |
|---|---|
| Synonyms | CHSY2, CSS3 |
| Function | Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1. |
| Cellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein |
| Tissue Location | Detected at low levels in brain, cerebral cortex, uterus and small intestine. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).[supplied by OMIM].
References
Izumikawa, T., et al. Biochem. J. 403(3):545-552(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Yada, T., et al. J. Biol. Chem. 278(41):39711-39725(2003)
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