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ST6GAL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P15907 |
| Other Accession | NP_775324.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46605 Da |
| Antigen Region | 178-206 aa |
| Gene ID | 6480 |
|---|---|
| Other Names | Beta-galactoside alpha-2, 6-sialyltransferase 1, Alpha 2, 6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1 |
| Target/Specificity | This ST6GAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human ST6GAL1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ST6GAL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ST6GAL1 |
|---|---|
| Synonyms | SIAT1 |
| Function | Transfers sialic acid from CMP-sialic acid to galactose- containing acceptor substrates. |
| Cellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Mondal, S., et al. Leuk. Res. 34(4):463-470(2010)
Lee, M., et al. Oncol. Rep. 23(3):757-761(2010)
Daly, A.K., et al. Nat. Genet. 41(7):816-819(2009)
Costa-Nogueira, C., et al. BMC Cancer 9, 431 (2009) :
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