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SUB1 Antibody(Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SUB1 Antibody(Center) AP19807c
    SUB1 Antibody (Center) (Cat. #AP19807c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SUB1 antibody detected the SUB1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P53999
Other Accession Q4R947, NP_006704.3
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 14395 Da
Antigen Region 18-47 aa
Additional Information
Gene ID 10923
Other Names Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14, SUB1, PC4, RPO2TC1
Target/Specificity This SUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human SUB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSUB1 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUB1
Synonyms PC4, RPO2TC1
Function General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Cellular Location Nucleus.
Citations (0)
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Background

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).

References

Das, C., et al. J. Mol. Biol. 397(1):1-12(2010)
Rajagopalan, S., et al. J. Biol. Chem. 284(32):21728-21737(2009)
Mortusewicz, O., et al. J. Cell Biol. 183(5):769-776(2008)
Batta, K., et al. Mol. Cell. Biol. 27(21):7603-7614(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 182.50
$ 70.00
Cat# AP19807c
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