GLT8D4 Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | A0PJZ3 |
Other Accession | NP_001073862.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 51056 Da |
Antigen Region | 404-432 aa |
Gene ID | 727936 |
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Other Names | Glucoside xylosyltransferase 2, 242n2, Glycosyltransferase 8 domain-containing protein 4, GXYLT2, GLT8D4 |
Target/Specificity | This GLT8D4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human GLT8D4. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GLT8D4 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GXYLT2 |
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Synonyms | GLT8D4 |
Function | Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. |
Cellular Location | Membrane; Single-pass type II membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
GXYLT2 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM 190198) (Sethi et al., 2010 [PubMed 19940119]).
References
Sethi, M.K., et al. J. Biol. Chem. 285(3):1582-1586(2010)
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