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Mouse Pbk Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q9JJ78 |
| Other Accession | NP_075698.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36745 Da |
| Antigen Region | 58-86 aa |
| Gene ID | 52033 |
|---|---|
| Other Names | Lymphokine-activated killer T-cell-originated protein kinase, PDZ-binding kinase, T-LAK cell-originated protein kinase, Pbk, Topk |
| Target/Specificity | This Mouse Pbk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of mouse Pbk. |
| Dilution | WB~~1:1000 IHC-P~~1:25 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Pbk Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pbk |
|---|---|
| Synonyms | Topk |
| Function | Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity).
References
Zykova, T.A., et al. Clin. Cancer Res. 12(23):6884-6893(2006)
Fujibuchi, T., et al. Dev. Growth Differ. 47(9):637-644(2005)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :
Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :
Easterday, M.C., et al. Dev. Biol. 264(2):309-322(2003)
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