Mouse Ei24 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q61070 |
Other Accession | Q4KM77, O14681, Q08DE5, NP_031941.1 |
Reactivity | Mouse |
Predicted | Bovine, Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38933 Da |
Antigen Region | 263-290 aa |
Gene ID | 13663 |
---|---|
Other Names | Etoposide-induced protein 24, p53-induced gene 8 protein, Ei24, Pig8 |
Target/Specificity | This Mouse Ei24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-290 amino acids from the C-terminal region of mouse Ei24. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Ei24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Ei24 |
---|---|
Synonyms | Pig8 |
Function | Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity). |
Cellular Location | Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Found in all the examined tissues. High expression was found in liver, skeletal muscle, pancreas, kidney heart and to a lesser extent in brain, placenta and lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ei24 may play a role in the cellular response to DNA damage and/or p53-mediated apoptosis.
References
Bahk, Y.Y., et al. J. Proteome Res. 9(10):5270-5283(2010)
Mork, C.N., et al. FEBS Lett. 581(28):5440-5444(2007)
Lee, J., et al. Mol. Cell Proteomics 6(4):669-676(2007)
Colombo, E., et al. Mol. Cell. Biol. 25(20):8874-8886(2005)
McClive, P.J., et al. Genesis 37(2):84-90(2003)
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