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FGF20 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FGF20 Antibody (C-term) AP19307b
    FGF20 Antibody (C-term)(Cat. #AP19307b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FGF20 antibody detected the FGF20 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NP95
Other Accession Q9EST9, Q9ESL9, NP_062825.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23499 Da
Antigen Region 136-165 aa
Additional Information
Gene ID 26281
Other Names Fibroblast growth factor 20, FGF-20, FGF20
Target/Specificity This FGF20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF20.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF20
Function Neurotrophic factor that regulates central nervous development and function.
Cellular Location Secreted.
Tissue Location Predominantly expressed in the cerebellum.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.

References

de Mena, L., et al. Neurosci. Lett. 479(1):22-25(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lemaitre, H., et al. J. Neurosci. 30(17):5992-5997(2010)
Maity, H., et al. Curr Pharm Biotechnol 10(6):609-625(2009)
Kalinina, J., et al. Mol. Cell. Biol. 29(17):4663-4678(2009)

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$ 365.00
$ 140.00
Cat# AP19307b
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