BCL2L12 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9HB09 |
Other Accession | NP_001035758.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26908 Da |
Antigen Region | 19-45 aa |
Gene ID | 83596 |
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Other Names | Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein, BCL2L12, BPR |
Target/Specificity | This BCL2L12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human BCL2L12. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BCL2L12 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BCL2L12 (HGNC:13787) |
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Synonyms | BPR |
Tissue Location | Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Florou, D., et al. Biochem. Biophys. Res. Commun. 391(1):214-218(2010)
Hong, Y., et al. Mol. Cell. Biochem. 333 (1-2), 323-330 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Thomadaki, H., et al. Ann. N. Y. Acad. Sci. 1171, 276-283 (2009) :
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