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TIMM50 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q3ZCQ8 |
| Other Accession | NP_001001563.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39646 Da |
| Antigen Region | 74-104 aa |
| Gene ID | 92609 |
|---|---|
| Other Names | Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50 |
| Target/Specificity | This TIMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human TIMM50. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TIMM50 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TIMM50 |
|---|---|
| Synonyms | TIM50 |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
| Tissue Location | Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Xu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :
Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)
Yuryev, A., et al. Genomics 81(2):112-125(2003)
Yamamoto, H., et al. Cell 111(4):519-528(2002)
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