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FLOT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75955 |
| Other Accession | Q9Z1E1, Q767L6, O08917, Q08DN8, NP_005794.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Pig, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47355 Da |
| Antigen Region | 104-133 aa |
| Gene ID | 10211 |
|---|---|
| Other Names | Flotillin-1, FLOT1 |
| Target/Specificity | This FLOT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human FLOT1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FLOT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FLOT1 |
|---|---|
| Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. |
| Cellular Location | Cell membrane; Peripheral membrane protein. Endosome Membrane, caveola {ECO:0000250|UniProtKB:O08917}; Peripheral membrane protein {ECO:0000250|UniProtKB:O08917}. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) Membrane-associated protein of caveola (By similarity) {ECO:0000250|UniProtKB:O08917, ECO:0000269|PubMed:17081065} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq].
References
Lee, B.Y., et al. Mol. Cell Proteomics 9(1):32-53(2010)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Saalik, P., et al. Bioconjug. Chem. 20(5):877-887(2009)
Rajendran, L., et al. PLoS ONE 4 (12), E8290 (2009) :
Rossy, J., et al. PLoS ONE 4 (4), E5403 (2009) :
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