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CNPY3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BT09 |
| Other Accession | NP_006577.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30748 Da |
| Antigen Region | 66-92 aa |
| Gene ID | 10695 |
|---|---|
| Other Names | Protein canopy homolog 3, CTG repeat protein 4a, Expanded repeat-domain protein CAG/CTG 5, Protein associated with TLR4, Trinucleotide repeat-containing gene 5 protein, CNPY3, CTG4A, ERDA5, PRAT4A, TNRC5 |
| Target/Specificity | This CNPY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the N-terminal region of human CNPY3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CNPY3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNPY3 |
|---|---|
| Synonyms | CTG4A, ERDA5, PRAT4A, TNRC5 |
| Function | Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity). |
| Cellular Location | Endoplasmic reticulum. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006 [PubMed 16849487]).
References
Wakabayashi, Y., et al. J. Immunol. 177(3):1772-1779(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)
Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)
Margolis, R.L., et al. Hum. Genet. 100(1):114-122(1997)
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