ESAM Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96AP7 |
Other Accession | Q95KI3, NP_620411.2 |
Reactivity | Human |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41176 Da |
Antigen Region | 259-289 aa |
Gene ID | 90952 |
---|---|
Other Names | Endothelial cell-selective adhesion molecule, ESAM |
Target/Specificity | This ESAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-289 amino acids from the C-terminal region of human ESAM. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ESAM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ESAM |
---|---|
Function | Can mediate aggregation most likely through a homophilic molecular interaction. |
Cellular Location | Cell junction, adherens junction {ECO:0000250|UniProtKB:Q925F2}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q925F2}. Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q925F2} |
Tissue Location | Highly expressed in endothelial cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ESAM can mediate aggregation most likely through a homophilic molecular interaction (By similarity).
References
Rohatgi, A., et al. Arterioscler. Thromb. Vasc. Biol. 29(10):1684-1690(2009)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nasdala, I., et al. J. Biol. Chem. 277(18):16294-16303(2002)
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