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RHOT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IXI2 |
| Other Accession | Q8BG51, Q6NVC5, Q5ZM73, Q2HJF8, NP_001028738.1 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Zebrafish, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70784 Da |
| Antigen Region | 84-110 aa |
| Gene ID | 55288 |
|---|---|
| Other Names | Mitochondrial Rho GTPase 1, MIRO-1, hMiro-1, 365-, Rac-GTP-binding protein-like protein, Ras homolog gene family member T1, RHOT1, ARHT1 |
| Target/Specificity | This RHOT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-110 amino acids from the N-terminal region of human RHOT1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RHOT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHOT1 |
|---|---|
| Synonyms | ARHT1 |
| Function | Mitochondrial GTPase involved in mitochondrial trafficking (PubMed:12482879, PubMed:16630562, PubMed:22396657). Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (PubMed:12482879, PubMed:16630562, PubMed:22396657). Promotes mitochondrial fission during high calcium conditions (PubMed:27716788). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Colocalizes with MGARP and RHOT2 at the mitochondria |
| Tissue Location | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
MacAskill, A.F., et al. Mol. Cell. Neurosci. 40(3):301-312(2009)
Wang, X., et al. Cell 136(1):163-174(2009)
Saotome, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(52):20728-20733(2008)
Fransson, S., et al. Biochem. Biophys. Res. Commun. 344(2):500-510(2006)
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