FRMD3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | A2A2Y4 |
Other Accession | NP_777598.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 68772 Da |
Antigen Region | 250-279 aa |
Gene ID | 257019 |
---|---|
Other Names | FERM domain-containing protein 3, Band 41-like protein 4O, Ovary type protein 41, 41O, FRMD3, EPB41L4O |
Target/Specificity | This FRMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human FRMD3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FRMD3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FRMD3 |
---|---|
Synonyms | EPB41L4O |
Function | Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. |
Cellular Location | Membrane; Single-pass membrane protein |
Tissue Location | Ovary-specific.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Protein 4.1 of red blood cells, or 4.1R (EPB41; MIM 130500), is a multifunctional protein essential for maintaining erythrocyte shape and membrane mechanical properties. The protein 4.1 family comprises a group of structural proteins that includes, in addition to 4.1R, 4.1G (general type; MIM 603237), 4.1B (brain type; MIM 605331), 4.1N (neuron type; MIM 602879), and 4.1O (ovary type).
References
Maeda, S., et al. Diabetes (2010) In press :
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Pezzolesi, M.G., et al. Diabetes 58(6):1403-1410(2009)
Haase, D., et al. Oncogene 26(30):4464-4468(2007)
Ni, X., et al. J. Hum. Genet. 48(2):101-106(2003)
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