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PTGFRN Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9P2B2 |
| Other Accession | NP_065173.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 98556 Da |
| Antigen Region | 458-485 aa |
| Gene ID | 5738 |
|---|---|
| Other Names | Prostaglandin F2 receptor negative regulator, CD9 partner 1, CD9P-1, Glu-Trp-Ile EWI motif-containing protein F, EWI-F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD315, PTGFRN, CD9P1, EWIF, FPRP, KIAA1436 |
| Target/Specificity | This PTGFRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-485 amino acids from the Central region of human PTGFRN. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PTGFRN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PTGFRN |
|---|---|
| Synonyms | CD9P1, EWIF, FPRP, KIAA1436 |
| Function | Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PTGFRN inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).
References
Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)
Andre, M., et al. J Proteomics 73(1):93-102(2009)
Andre, M., et al. Proteomics 7(21):3880-3895(2007)
Abache, T., et al. J. Cell. Biochem. 102(3):650-664(2007)
Sala-Valdes, M., et al. J. Biol. Chem. 281(28):19665-19675(2006)
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