GYG2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O15488 |
Other Accession | NP_001073324.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 55184 Da |
Antigen Region | 457-483 aa |
Gene ID | 8908 |
---|---|
Other Names | Glycogenin-2, GN-2, GN2, GYG2 |
Target/Specificity | This GYG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-483 amino acids from the C-terminal region of human GYG2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GYG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GYG2 |
---|---|
Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It self- glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. |
Tissue Location | Detected in liver (at protein level) (PubMed:9857012). Expressed preferentially in liver, heart, and pancreas (PubMed:9346895). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
References
Gibbons, B.J., et al. J. Mol. Biol. 319(2):463-477(2002)
Harris, R.A., et al. Proteomics 2(2):212-223(2002)
Zhai, L., et al. Gene 242 (1-2), 229-235 (2000) :
Mu, J., et al. J. Biol. Chem. 273(52):34850-34856(1998)
Orho, M., et al. J. Clin. Invest. 102(3):507-515(1998)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.