OCIAD1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9NX40 |
Other Accession | Q5XIG4, Q5E948, NP_001073308.1 |
Reactivity | Human |
Predicted | Bovine, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27626 Da |
Antigen Region | 184-210 aa |
Gene ID | 54940 |
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Other Names | OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen, OCIAD1, OCIA |
Target/Specificity | This OCIAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-210 amino acids from the C-terminal region of human OCIAD1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | OCIAD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OCIAD1 (HGNC:16074) |
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Function | Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946). |
Cellular Location | Endosome {ECO:0000250|UniProtKB:Q9CRD0}. |
Tissue Location | Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Wang, C., et al. Mol. Cancer Ther. 9(6):1709-1718(2010)
Sengupta, S., et al. Gynecol. Oncol. 109(2):226-233(2008)
Kim, J.M., et al. DNA Res. 13(6):275-286(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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