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ZKSCAN4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q969J2 |
| Other Accession | NP_061983.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61579 Da |
| Antigen Region | 446-473 aa |
| Gene ID | 387032 |
|---|---|
| Other Names | Zinc finger protein with KRAB and SCAN domains 4, P373c61, Zinc finger protein 307, Zinc finger protein 427, ZKSCAN4, ZNF307, ZNF427 |
| Target/Specificity | This ZKSCAN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-473 amino acids from the C-terminal region of human ZKSCAN4. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZKSCAN4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZKSCAN4 |
|---|---|
| Synonyms | ZNF307, ZNF427 |
| Function | May be involved in the transcriptional activation of MDM2 and EP300 genes. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187, ECO:0000269|PubMed:17910948} |
| Tissue Location | Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZKSCAN4 may be involved in the transcriptional activation of MDM2 and EP300 genes.
References
Ecker, K., et al. J. Mol. Endocrinol. 42(2):105-117(2009)
Li, J., et al. Biochem. Biophys. Res. Commun. 363(4):895-900(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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