MDH2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P40926 |
Other Accession | Q4R568, NP_005909.2 |
Reactivity | Human |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 35503 Da |
Antigen Region | 297-326 aa |
Gene ID | 4191 |
---|---|
Other Names | Malate dehydrogenase, mitochondrial, MDH2 |
Target/Specificity | This MDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human MDH2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MDH2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MDH2 |
---|---|
Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:P04636} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. [provided by RefSeq].
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Rzem, R., et al. J. Inherit. Metab. Dis. 30(5):681-689(2007)
Luo, C., et al. J. Biochem. Biophys. Methods 68(2):101-111(2006)
Kullberg, M., et al. Mol. Biol. Evol. 23(8):1493-1503(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
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