BRI3BP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8WY22 |
Other Accession | NP_542193.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27836 Da |
Antigen Region | 157-183 aa |
Gene ID | 140707 |
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Other Names | BRI3-binding protein, I3-binding protein, Cervical cancer 1 proto-oncogene-binding protein KG19, HCCRBP-1, BRI3BP {ECO:0000312|EMBL:AAL543821} |
Target/Specificity | This BRI3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-183 amino acids from the Central region of human BRI3BP. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BRI3BP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BRI3BP {ECO:0000312|EMBL:AAL54382.1} |
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Function | Involved in tumorigenesis and may function by stabilizing p53/TP53. |
Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein |
Tissue Location | Most abundantly expressed in brain, liver and kidney (PubMed:11860200). Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas (PubMed:17943721) |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF688 is involved in tumorigenesis and may function by stabilizing TP53/p53.
References
Yamazaki, T., et al. Biochem. Biophys. Res. Commun. 362(4):971-975(2007)
Lin, L., et al. Biochem. Genet. 39 (11-12), 369-377 (2001) :
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