PNMA3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9UL41 |
Other Accession | NP_037496.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52376 Da |
Antigen Region | 384-412 aa |
Gene ID | 29944 |
---|---|
Other Names | Paraneoplastic antigen Ma3, PNMA3, MA3 |
Target/Specificity | This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PNMA3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PNMA3 |
---|---|
Synonyms | MA3 |
Cellular Location | Nucleus, nucleolus. |
Tissue Location | Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq].
References
Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006)
Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :
Rosenfeld, M.R., et al. Ann. Neurol. 50(3):339-348(2001)
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