ZC3H7A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8IWR0 |
Other Accession | NP_054872.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 110538 Da |
Antigen Region | 563-589 aa |
Gene ID | 29066 |
---|---|
Other Names | Zinc finger CCCH domain-containing protein 7A, ZC3H7A, ZC3H7, ZC3HDC7 |
Target/Specificity | This ZC3H7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-589 amino acids from the Central region of human ZC3H7A. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZC3H7A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZC3H7A |
---|---|
Synonyms | ZC3H7, ZC3HDC7 |
Function | May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'- ATA(A/T)-5' motif in the apical loop. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZC3H7A is part of a novel CCCH zinc finger protein family, which plays a role in the regulation of macrophage activation.
References
Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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