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OXTR Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P30559 |
| Other Accession | NP_000907.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42772 Da |
| Antigen Region | 8-36 aa |
| Gene ID | 5021 |
|---|---|
| Other Names | Oxytocin receptor, OT-R, OXTR |
| Target/Specificity | This OXTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human OXTR. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | OXTR Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OXTR |
|---|---|
| Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
References
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Kim, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15717-15721(2010)
Thompson, R.J., et al. Psychoneuroendocrinology (2010) In press :
Tost, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13936-13941(2010)
Amrani, Y., et al. Respir. Res. 11, 104 (2010) :
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