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OXTR Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OXTR Antibody (N-term) AP17658a
    OXTR Antibody (N-term) (Cat. #AP17658a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OXTR antibody detected the OXTR protein (arrow).
    detail
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30559
Other Accession NP_000907.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42772 Da
Antigen Region 8-36 aa
Additional Information
Gene ID 5021
Other Names Oxytocin receptor, OT-R, OXTR
Target/Specificity This OXTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human OXTR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOXTR Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OXTR
Function Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations ( 0 )

Background

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.

References

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Kim, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15717-15721(2010)
Thompson, R.J., et al. Psychoneuroendocrinology (2010) In press :
Tost, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13936-13941(2010)
Amrani, Y., et al. Respir. Res. 11, 104 (2010) :

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$ 365.00
$ 140.00
Cat# AP17658a
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