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SKAP2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75563 |
| Other Accession | Q920G0, Q3UND0, Q32LP7, NP_003921.2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41217 Da |
| Antigen Region | 137-165 aa |
| Gene ID | 8935 |
|---|---|
| Other Names | Src kinase-associated phosphoprotein 2, Pyk2/RAFTK-associated protein, Retinoic acid-induced protein 70, SKAP55 homolog, SKAP-55HOM, SKAP-HOM, Src family-associated phosphoprotein 2, Src kinase-associated phosphoprotein 55-related protein, Src-associated adapter protein with PH and SH3 domains, SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R |
| Target/Specificity | This SKAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the Central region of human SKAP2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SKAP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SKAP2 |
|---|---|
| Synonyms | PRAP, RA70, SAPS, SCAP2, SKAP55R |
| Function | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Ubiquitously expressed. Present in platelets (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Qu, H.Q., et al. Hum. Mol. Genet. 19(12):2534-2538(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
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