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BMP15 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | O95972 |
| Other Accession | NP_005439 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45055 Da |
| Antigen Region | 241-271 aa |
| Gene ID | 9210 |
|---|---|
| Other Names | Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF-9B, BMP15, GDF9B |
| Target/Specificity | This BMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-271 amino acids from the Central region of human BMP15. |
| Dilution | WB~~1:2000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BMP15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BMP15 |
|---|---|
| Synonyms | GDF9B |
| Function | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Bmp15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that Bmp15 may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9.
References
Liao, W.X., et al., J. Biol. Chem. 278(6):3713-3719 (2003).
Moore, R.K., et al., J. Biol. Chem. 278(1):304-310 (2003).
Galloway, S.M., et al., Nat. Genet. 25(3):279-283 (2000).
Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84(8):2744-2750 (1999).
Dube, J.L., et al., Mol. Endocrinol. 12(12):1809-1817 (1998).
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