SEPT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8WYJ6 |
Other Accession | NP_443070.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 42386 Da |
Antigen Region | 54-82 aa |
Gene ID | 1731 |
---|---|
Other Names | Septin-1, LARP, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24, SEPT1, DIFF6, PNUTL3 |
Target/Specificity | This SEPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human SEPT1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SEPT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SEPTIN1 (HGNC:2879) |
---|---|
Synonyms | DIFF6, PNUTL3, SEPT1 |
Function | Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis |
Tissue Location | Expressed at high levels in lymphoid and hematopoietic tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene encodes a protein associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. [provided by RefSeq].
References
Kato, Y., et al. Int. J. Oncol. 31(5):1021-1028(2007)
Steels, J.D., et al. Cell Motil. Cytoskeleton 64(10):794-807(2007)
Qi, M., et al. Biochem. Biophys. Res. Commun. 336(3):994-1000(2005)
Qi, M., et al. Biochem. Biophys. Res. Commun. 336(3):994-1000(2005)
Scanlan, M.J., et al. Cancer Immun. 1, 4 (2001) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.