MRC1L1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P22897 |
Other Accession | Q5VSK2, NP_001009567.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 166012 Da |
Antigen Region | 359-388 aa |
Gene ID | 4360 |
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Other Names | Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1 |
Target/Specificity | This MRC1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the N-terminal region of human MRC1L1. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MRC1L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRC1 |
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Synonyms | CLEC13D, CLEC13DL, MRC1L1 |
Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. |
Cellular Location | Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a type I membrane receptor protein highly related to the mannose receptor C type 1 protein (MRC1). The two genes are located near each other on chromosome 10 in a region thought to represent a segmental duplication.
References
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
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