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SNAPC2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q13487 |
| Other Accession | NP_003074.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35556 Da |
| Antigen Region | 278-307 aa |
| Gene ID | 6618 |
|---|---|
| Other Names | snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit, SNAPC2, SNAP45 |
| Target/Specificity | This SNAPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human SNAPC2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SNAPC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SNAPC2 |
|---|---|
| Synonyms | SNAP45 |
| Function | Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SNAPC2 is a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
References
Shanmugam, M., et al. J. Biol. Chem. 283(21):14845-14856(2008)
Emran, F., et al. Gene 377, 96-108 (2006) :
Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
Acierno, J.S. Jr., et al. Genomics 73(2):203-210(2001)
Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)
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