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SNAPC2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - SNAPC2 Antibody (C-term) AP16427b
    SNAPC2 Antibody (C-term) (Cat. #AP16427b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SNAPC2 antibody detected the SNAPC2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q13487
Other Accession NP_003074.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35556 Da
Antigen Region 278-307 aa
Additional Information
Gene ID 6618
Other Names snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit, SNAPC2, SNAP45
Target/Specificity This SNAPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human SNAPC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNAPC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNAPC2
Synonyms SNAP45
Function Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

SNAPC2 is a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

References

Shanmugam, M., et al. J. Biol. Chem. 283(21):14845-14856(2008)
Emran, F., et al. Gene 377, 96-108 (2006) :
Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
Acierno, J.S. Jr., et al. Genomics 73(2):203-210(2001)
Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)

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$ 365.00
$ 140.00
Cat# AP16427b
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