ARMT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9H993 |
Other Accession | Q6AYT5, NP_078849.1 |
Reactivity | Human |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 51172 Da |
Antigen Region | 29-57 aa |
Gene ID | 79624 |
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Other Names | UPF0364 protein C6orf211, C6orf211 |
Target/Specificity | This ARMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human ARMT1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ARMT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ARMT1 {ECO:0000303|PubMed:25732820, ECO:0000312|HGNC:HGNC:17872} |
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Function | Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). Its preference for fructose-1- phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity). Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (PubMed:25732820). Possibly methylates PCNA, suggesting it is involved in the DNA damage response (PubMed:25732820). |
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Provided below are standard protocols that you may find useful for product applications.
References
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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