Mouse Cabc1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q60936 |
Other Accession | Q5BJQ0, NP_075830.2, NP_001156762.1 |
Reactivity | Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 71743 Da |
Antigen Region | 396-423 aa |
Gene ID | 67426 |
---|---|
Other Names | Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, Adck3, Cabc1 |
Target/Specificity | This Mouse Cabc1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of mouse Cabc1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Cabc1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Coq8a {ECO:0000250|UniProtKB:Q8NI60} |
---|---|
Function | Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity). |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q8NI60}. Membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8NI60, ECO:0000255} |
Tissue Location | Present in various tissues (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Cabc1 may be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.
References
Pagliarini, D.J., et al. Cell 134(1):112-123(2008)
Garcia-Frigola, C., et al. Brain Res. Mol. Brain Res. 122(2):133-150(2004)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.