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NFIC Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P08651 |
| Other Accession | NP_995315.1, NP_005588.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55675 Da |
| Antigen Region | 180-208 aa |
| Gene ID | 4782 |
|---|---|
| Other Names | Nuclear factor 1 C-type, NF1-C, Nuclear factor 1/C, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/C, NF-I/C, NFI-C, TGGCA-binding protein, NFIC, NFI |
| Target/Specificity | This NFIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-208 amino acids from the Central region of human NFIC. |
| Dilution | IF~~1:10~50 WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NFIC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NFIC |
|---|---|
| Synonyms | NFI |
| Function | Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NFIC recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Nilsson, J., et al. Cancer Res. 70(5):2020-2029(2010)
Udelhoven, M., et al. J. Mol. Endocrinol. 44(2):99-113(2010)
Plasari, G., et al. Mol. Cell. Biol. 29(22):6006-6017(2009)
Riffel, A.K., et al. Mol. Pharmacol. 76(5):1104-1114(2009)
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