PNLIP Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P16233 |
Other Accession | NP_000927.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 51157 Da |
Antigen Region | 312-341 aa |
Gene ID | 5406 |
---|---|
Other Names | Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase, PNLIP |
Target/Specificity | This PNLIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human PNLIP. |
Dilution | WB~~1:1000 IHC-P~~1:100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PNLIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PNLIP (HGNC:9155) |
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Function | Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas.
References
Colin, D.Y., et al. Protein Eng. Des. Sel. 23(5):365-373(2010)
Ranaldi, S., et al. Biochemistry 49(10):2140-2149(2010)
Bourbon-Freie, A., et al. J. Biol. Chem. 284(21):14157-14164(2009)
Ranaldi, S., et al. Biochemistry 48(3):630-638(2009)
Colin, D.Y., et al. Biochem. Biophys. Res. Commun. 370(3):394-398(2008)
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