FAM83A Antibody (Center D283)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q86UY5 |
Other Accession | NP_116288.2, NP_996889.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 47458 Da |
Antigen Region | 268-295 aa |
Gene ID | 84985 |
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Other Names | Protein FAM83A, Tumor antigen BJ-TSA-9, Tumor-specific gene expressed in prostate protein, FAM83A, TSGP |
Target/Specificity | This FAM83A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-295 amino acids from the Central region of human FAM83A. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FAM83A Antibody (Center D283) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FAM83A (HGNC:28210) |
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Function | Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
References
Liu, L., et al. Biochem. Biophys. Res. Commun. 372(4):756-760(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Li, Y., et al. Neoplasia 7(12):1073-1080(2005)
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