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Actin (ACTB/ACTC) Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 4
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P68032 |
| Other Accession | P60010, P68136, P68135, P68137, P68134, P68133, P68139, P68138, P63269, P63268, P63267, P63270, Q5E9B5, A2BDB0, P63259, P63260, P63261, Q5ZMQ2, P63258, P04751, P68035, P68033, P68034, Q3ZC07, O93400, P60711, P29751, Q6QAQ1, P60710, Q4R561, P60709, P48975 |
| Reactivity | Human, Mouse |
| Predicted | C.Elegans, Drosophila, Xenopus, Chicken, Bovine, Rabbit, Rat, Zebrafish, Hamster, Horse, Monkey, Pig, Sheep, Yeast |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42019 Da |
| Antigen Region | 38-67 aa |
| Gene ID | 70 |
|---|---|
| Other Names | Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC |
| Target/Specificity | This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC). |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Actin (ACTB/ACTC) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACTC1 |
|---|---|
| Synonyms | ACTC |
| Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Cellular Location | Cytoplasm, cytoskeleton. |
Provided below are standard protocols that you may find useful for product applications.
Background
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
References
Villebeck,L., Biochemistry 46 (44), 12639-12647 (2007) Avizienyte,E., Exp. Cell Res. 313 (15), 3175-3188 (2007) Bouldin,A.A., Muscle Nerve 35 (2), 254-258 (2007)
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