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LY86 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O95711 |
| Other Accession | O88188, NP_004262.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 17906 Da |
| Antigen Region | 98-127 aa |
| Gene ID | 9450 |
|---|---|
| Other Names | Lymphocyte antigen 86, Ly-86, Protein MD-1, LY86, MD1 |
| Target/Specificity | This LY86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the C-terminal region of human LY86. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LY86 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LY86 |
|---|---|
| Synonyms | MD1 |
| Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity). |
| Cellular Location | Secreted, extracellular space. Note=Associated with CD180 at the cell surface |
| Tissue Location | Highly expressed in B-cells, monocytes and tonsil. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
LY86 may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Shyn, S.I., et al. Mol. Psychiatry (2009) In press :
Lee, S.W., et al. J Microbiol Immunol Infect 41(6):445-449(2008)
Wang, J.Y., et al. Int. J. Immunogenet. 34(6):407-412(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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