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TGF Beta 2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - TGF Beta 2 Antibody (C-term) AP1476b
    TGFB2 Antibody (C-term) (Cat.# AP1476b) western blot analysis in Raji cell line lysates (35ug/lane).This demonstrates the TGFB2 antibody detected the TGFB2 protein (arrow).
    detail
  • IHC-P - TGF Beta 2 Antibody (C-term) AP1476b
    Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with TGFB2 antibody (C-term)(Cat.#AP1476b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P61812
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47748 Da
Antigen Region 277-306 aa
Additional Information
Gene ID 7042
Other Names Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2
Target/Specificity This TGF Beta 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human TGF Beta 2.
Dilution WB~~1:1000
IHC-P~~1:50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTGF Beta 2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TGFB2
Function [Transforming growth factor beta-2 proprotein]: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
Cellular Location [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P01137}
Research Areas
Citations (0)
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Background

Transforming growth factor-beta 2 (TGF-?2) is a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene.

References

Hatsushika,K., Clin. Exp. Allergy 37 (8), 1165-1174 (2007) Jimi,S., Int. J. Oncol. 31 (2), 397-404 (2007) Ito,T., Biochem. Biophys. Res. Commun. 359 (1), 108-114 (2007) Yao,K., Mol. Vis. 13, 1769-1776 (2007)

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$ 365.00
$ 140.00
Cat# AP1476b
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