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VAMP3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q15836 |
| Other Accession | P63025, P63024, Q4R8T0, Q2KJD2, P63045, P63044, P63027, P63026, Q63666, Q62442, P23763, Q0V7N0, NP_004772.1 |
| Reactivity | Human, Mouse, Zebrafish |
| Predicted | Bovine, Rat, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 11309 Da |
| Antigen Region | 15-43 aa |
| Gene ID | 9341 |
|---|---|
| Other Names | Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3 |
| Target/Specificity | This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | VAMP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | VAMP3 |
|---|---|
| Synonyms | SYB3 |
| Function | SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. |
| Cellular Location | Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Synapse, synaptosome |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
References
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Fader, C.M., et al. Biochim. Biophys. Acta 1793(12):1901-1916(2009)
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
Vassilopoulos, S., et al. Science 324(5931):1192-1196(2009)
Luftman, K., et al. Biochem. Biophys. Res. Commun. 380(1):65-70(2009)
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