MIPEP Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q99797 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 80641 Da |
Antigen Region | 180-209 aa |
Gene ID | 4285 |
---|---|
Other Names | Mitochondrial intermediate peptidase, MIP, MIPEP, MIP |
Target/Specificity | This MIPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-209 amino acids from the N-terminal region of human MIPEP. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MIPEP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MIPEP |
---|---|
Synonyms | MIP |
Function | Cleaves proteins, imported into the mitochondrion, to their mature size. |
Cellular Location | Mitochondrion matrix. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MIPEP performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This protein may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia.
References
Chew A., Genomics 40:493-496(1997).
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