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SEMG1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SEMG1 Antibody (N-term) AP14543a
    SEMG1 Antibody (N-term) (Cat. #AP14543a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SEMG1 antibody detected the SEMG1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P04279
Other Accession NP_002998.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 52131 Da
Antigen Region 92-121 aa
Additional Information
Gene ID 6406
Other Names Semenogelin-1, Semenogelin I, SGI, Alpha-inhibin-92, Alpha-inhibin-31, Seminal basic protein, SEMG1, SEMG
Target/Specificity This SEMG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human SEMG1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEMG1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEMG1
Synonyms SEMG
Function Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.
Cellular Location Secreted.
Tissue Location Seminal vesicle.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.

References

Mitra, A., et al. Biol. Reprod. 82(3):489-496(2010)
Yoshida, K., et al. Cell Motil. Cytoskeleton 66(2):99-108(2009)
Ahmed, S.U., et al. Cytotherapy 11(2):238-244(2009)
Edstrom, A.M., et al. J. Immunol. 181(5):3413-3421(2008)
Emami, N., et al. J. Biol. Chem. 283(28):19561-19569(2008)

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$ 182.50
$ 70.00
Cat# AP14543a
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