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AATK Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - AATK Antibody (N-term) AP14516a
    AATK Antibody (N-term) (Cat. #AP14516a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the AATK antibody detected the AATK protein (arrow).
    detail
  • WB - AATK Antibody (N-term) AP14516a
    All lanes : Anti-AATK Antibody (N-term) at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lane 3: A549 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 145 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6ZMQ8
Other Accession NP_001073864.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 144569 Da
Antigen Region 46-74 aa
Additional Information
Gene ID 9625
Other Names Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1
Target/Specificity This AATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human AATK.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAATK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AATK
Synonyms AATYK, KIAA0641, LMR1, LMTK1
Function May be involved in neuronal differentiation.
Cellular Location Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear
Tissue Location Expressed in brain..
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.

References

Tomomura, M., et al. Neuroscience 148(2):510-521(2007)
Lee, S., et al. Oncol. Rep. 16(4):747-754(2006)
Honma, N., et al. Biochem. Biophys. Res. Commun. 310(2):398-404(2003)
Tomomura, M., et al. Brain Res. Mol. Brain Res. 112 (1-2), 103-112 (2003) :
Tomomura, M., et al. Oncogene 20(9):1022-1032(2001)

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$ 365.00
$ 140.00
Cat# AP14516a
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