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GTF2E1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P29083 |
| Other Accession | A6QLI8, NP_005504.2 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49452 Da |
| Antigen Region | 93-121 aa |
| Gene ID | 2960 |
|---|---|
| Other Names | General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1 |
| Target/Specificity | This GTF2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the N-terminal region of human GTF2E1. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GTF2E1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GTF2E1 |
|---|---|
| Synonyms | TF2E1 |
| Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
References
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Okuda, M., et al. EMBO J. 27(7):1161-1171(2008)
Di Lello, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105(1):106-111(2008)
Jawhari, A., et al. EMBO Rep. 7(5):500-505(2006)
Okuda, M., et al. J. Biol. Chem. 279(49):51395-51403(2004)
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