Rax Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9Y2V3 |
Other Accession | Q9JLT7, O35602 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36676 Da |
Antigen Region | 315-346 aa |
Gene ID | 30062 |
---|---|
Other Names | Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX |
Target/Specificity | This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-346 amino acids from the C-terminal region of human Rax. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Rax Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RAX |
---|---|
Synonyms | RX |
Function | Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE- 1/Ret 1) in the photoreceptor cell-specific arrestin promoter. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the developing eye and weakly expressed in the adult retina |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
References
Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)
Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)
Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)
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