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Rax Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Rax Antibody (N-term) AP1428a
    Western blot analysis of anti-Rax Pab (Cat.#AP1428a) in mouse brain tissue lysates (35ug/lane). Rax(arrow) was detected using the purified Pab.
    detail
  • IHC-P - Rax Antibody (N-term) AP1428a
    Formalin-fixed and paraffin-embedded human brain tissue reacted with Rax Antibody (N-term) (Cat.#AP1428a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9Y2V3
Other Accession Q9PVX0
Reactivity Human, Mouse
Predicted Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36676 Da
Antigen Region 15-46 aa
Additional Information
Gene ID 30062
Other Names Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX
Target/Specificity This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-46 amino acids from the N-terminal region of human Rax.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRax Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAX
Synonyms RX
Function Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE- 1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Cellular Location Nucleus.
Tissue Location Expressed in the developing eye and weakly expressed in the adult retina
Citations (0)
citation

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Background

Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.

References

Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)
Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)
Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)

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$ 365.00
$ 140.00
Cat# AP1428a
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