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NR2F2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P24468 |
| Other Accession | O09018, P43135, Q9TTR7, NP_066285.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45571 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 7026 |
|---|---|
| Other Names | COUP transcription factor 2, COUP-TF2, Apolipoprotein A-I regulatory protein 1, ARP-1, COUP transcription factor II, COUP-TF II, Nuclear receptor subfamily 2 group F member 2, NR2F2, ARP1, TFCOUP2 |
| Target/Specificity | This NR2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NR2F2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NR2F2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NR2F2 |
|---|---|
| Synonyms | ARP1, TFCOUP2 |
| Function | Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:29478779). |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Kang, J., et al. Blood 116(1):140-150(2010)
Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :
Hubert, M.A., et al. PLoS ONE 5 (2), E9417 (2010) :
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