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NPFFR1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9GZQ6 |
| Other Accession | NP_071429.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47819 Da |
| Antigen Region | 337-366 aa |
| Gene ID | 64106 |
|---|---|
| Other Names | Neuropeptide FF receptor 1, G-protein coupled receptor 147, RFamide-related peptide receptor OT7T022, NPFFR1, GPR147, NPFF1 |
| Target/Specificity | This NPFFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human NPFFR1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NPFFR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPFFR1 (HGNC:17425) |
|---|---|
| Synonyms | GPR147, NPFF1 |
| Function | Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ubuka, T., et al. PLoS ONE 4 (12), E8400 (2009) :
Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Bonini, J.A., et al. J. Biol. Chem. 275(50):39324-39331(2000)
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