18,000+ products cover the ten top research categories, including cancer, metabolism, cardiovascular, neuroscience, and stem cells. Each antibody is crafted with care according to rigorous protocols for immunogen design and preparation, presentation to host animal, and high-affinity purification against the antigen. Quality is embedded in the production process to assure the best antibody for you.
Crown antibodies pass additional stringent quality requirements, including extended control sets, uniform results against multiple biologically relevant cell lines and tissues, and function in multiple applications.
Abgent develops 1000+ new products per year. We provide tools for path-breaking research by developing antibodies that detect a comprehensive library of novel and established targets. For established targets we seek to add antibodies that recognize new epitopes, including post-translational modifications such as phosphorylation and methylation. For new targets we consult with leading experts to accelerate development of antibodies that will propel state-of-the-art research in cellular health and disease.
Individual peptides for SARS-CoV-2 Spike glycoprotein. In order to study the specificity of cellular immune responses against SARS CoV-2 and potential immunity caused by other human Corona Viruses, Abcepta provides Spike peptide individually, as pools and in plate. These peptides can be used for antigen specific T-cell stimulation in T-cell assays or T-cell expansion.
All peptides are manufactured in the San Diego, California. Custom peptide services include long peptides (>100 aa), cyclic peptides, difficult sequences, fluorescent labels, phospho-peptides and other post-translational modifications.
The majority of Abcepta antibodies are produced using peptide immunogens. These immuno-specific peptides can be used as blocking agents when using the complementary antibodies in a range of applications.
Abcepta's portfolio of cell lines, tissues and lysates are drawn from a range of species and immortalized cell lines. All our cell lines and lysates are validated in key applications.
These tissue lysates can be used in applications such as SDS-PAGE and Western blotting. Whole cell lysates can be used as positive controls for applications such as ELISAs, immunoprecipitation (IP) and Western blotting.
Obtaining high-quality whole cell lysates can be tedious as well as time consuming. Abcepta offers a comprehensive portfolio of whole cell lysates for research use.
Browse our catalog to find the right whole cell lysate for your experiment.
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Abcepta is a leading manufacturer of primary antibodies with more than fifteen years of experience. We supply quality antibodies and related products drug discovery and academic laboratories worldwide. Our focus is on targets covering the major research areas impacting health and disease, including cancer, metabolism, cardiovascular, neuroscience, and stem cells.
Founded in 2001, Abcepta is one of the world's largest manufacturers of research user only antibodies. WuXi Apptec, a leading global contract R&D services provider serving the pharmaceutical, biotech, and medical device industries, acquired Abcepta in October of 2011.
With its history as an original manufacturer, Abcepta has a deep and practical understanding of the production process for antibodies, peptides, and recombinant proteins. We have assembled world-class, independently credentialed facilities, operate under a strict project management paradigm with highly trained staff, rigorously test our products in-process and post-production, and monitor customer feedback to assure that we earn the trust of scientists who choose to work with us.
Abcepta may in-licenses select products and technologies to offer our customers a wide variety of options for their proteomic research needs. Contact us for further information and non-disclosure agreements. Our experienced discovery and production teams will work with you to jointly evaluate proposals and identify partnering opportunities.
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The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
WNT3 Antibody (Center) (Cat. #AP14130c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the WNT3 antibody detected the WNT3 protein (arrow).
WNT3 Antibody (Center) (Cat. #AP14130c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the WNT3 antibody detected the WNT3 protein (arrow).
This WNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the Central region of human WNT3.
Dilution
WB~~1:1000
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
WNT3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name
WNT3
Synonyms
INT4
Function
Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:26902720). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge (By similarity). Required for normal embryonic development, and especially for limb development (PubMed:14872406).
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to info@abcepta.com, and receive a free "I Love Antibodies" mug.
Citations for related products
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
The WNT gene family consists of structurally related genes
which encode secreted signaling proteins. These proteins have been
implicated in oncogenesis and in several developmental processes,
including regulation of cell fate and patterning during
embryogenesis. This gene is a member of the WNT gene family. It
encodes a protein which shows 98% amino acid identity to mouse Wnt3
protein, and 84% to human WNT3A protein, another WNT gene product.
The mouse studies show the requirement of Wnt3 in primary axis
formation in the mouse. Studies of the gene expression suggest that
this gene may play a key role in some cases of human breast,
rectal, lung, and gastric cancer through activation of the
WNT-beta-catenin-TCF signaling pathway. This gene is clustered with
WNT15, another family member, in the chromosome 17q21 region.
References
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Memarian, A., et al. Leuk. Lymphoma 50(12):2061-2070(2009)
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