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CPO Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IVL8 |
| Other Accession | NP_775100.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42529 Da |
| Antigen Region | 46-75 aa |
| Gene ID | 130749 |
|---|---|
| Other Names | Carboxypeptidase O, CPO, 3417-, CPO |
| Target/Specificity | This CPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human CPO. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CPO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CPO (HGNC:21011) |
|---|---|
| Function | Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues. |
| Cellular Location | Apical cell membrane; Lipid-anchor, GPI-anchor |
| Tissue Location | Detected in enterocytes of the ileum. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Probable carboxypeptidase which may cleave proteins with C-terminal acidic residues (By similarity).
References
Hillier, L.W., et al. Nature 434(7034):724-731(2005) Wei, S., et al. J. Biol. Chem. 277(17):14954-14964(2002)
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