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CYB5A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P00167 |
| Other Accession | NP_001905.1, NP_001177736.1, NP_683725.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 15330 Da |
| Antigen Region | 69-98 aa |
| Gene ID | 1528 |
|---|---|
| Other Names | Cytochrome b5, Microsomal cytochrome b5 type A, MCB5, CYB5A, CYB5 |
| Target/Specificity | This CYB5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CYB5A. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CYB5A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CYB5A |
|---|---|
| Synonyms | CYB5 |
| Function | Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. |
| Cellular Location | [Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
References
Gardner, A.M., et al. J. Biol. Chem. 285(31):23850-23857(2010)
Kok, R.C., et al. J. Clin. Endocrinol. Metab. 95(3):994-999(2010)
Sacco, J.C., et al. Pharmacogenet. Genomics 20(1):26-37(2010)
Maghzal, G.J., et al. J. Biol. Chem. 283(18):12014-12025(2008)
Inui, H., et al. Biochemistry 46(35):10213-10221(2007)
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